Albumin-Adjusted Calcium and Ionized Calcium

pH-adjusted ionized calcium

Albumin-corrected calcium and ionized calcium in stable haemodialysis patients.

BACKGROUND It is ionized calcium that is physiologically active and under homeostatic control; however, total calcium is more conveniently measured. Formulae for correction of calcium to account for albumin binding have not been validated in a dialysis setting. METHODS We measured ionized calcium simultaneously with total calcium (t[Ca]), albumin, total protein and pH before dialysis in 50 st...

Actual ionized calcium (at actual pH) vs adjusted ionized calcium (at pH 7.4) in hemodialyzed patients.

typed double-spaced (including references) with conventional margins. The overall length is limited to five manuscript pages, including not more than one figure or one table. To the Editor: Ionized calcium is now the measurement of choice for evaluating calcium metabolic diseases (1, 2). Ionized calcium may be reported either as the actual ionized calcium, referred to the actual pH of the patie...

Ionized calcium

Albumin-adjusted calcium concentration in serum increases during normal pregnancy.

Concentrations of total calcium and albumin were measured in serum specimens from 41 women at intervals before, during, and after 42 pregnancies. The albumin concentration decreased but the calcium decreased more slowly, so that the albumin-adjusted calcium concentration increased from conception to term. These findings, taken in conjunction with published observations of hypercalciuria, increa...